HitPredict

Interactor 1: STAU1 (O95793)
Double-stranded RNA-binding protein Staufen homolog 1
Gene: STAU1

Interactor 2: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30948266, 36232890, 23125841
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 577 Hs			1 372
+	Hs
		161925 STAU1_HUMAN (1-577): 0: 524: 100.00		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		322185 STAU1_HUMAN (1-577): 0: 524: 100.00		ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00
+	Hs
		322361 STAU1_HUMAN (1-577): 0: 524: 100.00		ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71
+	Hs
		323049 STAU1_HUMAN (1-577): 0: 524: 100.00		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		322606 STAU1_HUMAN (1-577): 0: 524: 100.00		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		322569 STAU1_HUMAN (1-577): 0: 524: 100.00		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		453558 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		201705 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87
+	Hs
		453237 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		161997 DSRAD_HUMAN (246-572): 7.91e-51: 191: 16.57		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		453278 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		944810 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44
+	Hs
		1020315 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98
+	Hs
		162010 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41
+	Hs
		1048193 STRBP_HUMAN (48-336): 1.3e-63: 223: 17.33		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		944907 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44
+	Hs
		269714 PRKRA_HUMAN (67-353): 1.54e-30: 123: 19.42		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98
+	Hs
		944775 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00
+	Hs
		944766 RED1_HUMAN (254-488): 1.1e-31: 132: 17.92		PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56
+	Hs
		1020337 STAU2_HUMAN (177-569): 4.96e-21: 99: 16.46		ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98