HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 21203488
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 466 Hs			1 906
+	Hs
		610513 KRT84_HUMAN (12-434): 2.04e-96: 304: 31.93		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610433 K2C79_HUMAN (6-422): 3.56e-83: 267: 30.59		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		380445 K2C6B_HUMAN (68-430): 5.13e-73: 242: 33.42		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610295 K2C6C_HUMAN (68-430): 9.35e-73: 241: 33.70		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		531534 K2C5_HUMAN (68-414): 4.76e-72: 240: 34.66		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		359466 K2C6A_HUMAN (68-430): 1.62e-71: 238: 32.88		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		203197 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		SYNJ1_HUMAN (542-897): 2.72e-14: 79.6: 10.22
+	Hs
		409194 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25
+	Hs
		203211 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		SYNJ1_HUMAN (542-897): 2.72e-14: 79.6: 10.22
+	Hs
		781964 PERI_HUMAN (7-462): 7.65e-130: 385: 58.08		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25
+	Hs
		203200 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		SYNJ1_HUMAN (542-897): 2.72e-14: 79.6: 10.22
+	Hs
		580149 K2C4_HUMAN (4-430): 2.28e-79: 257: 30.70		ASPP1_HUMAN (445-844): 1.47e-10: 67.3: 10.25