HitPredict

Interactor 1: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27684187, 38280479
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WW~WW
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 575 Hs			1 504
+	Hs
		324607 BAG3_HUMAN (1-575): 0: 809: 100.00		WWTR1_HUMAN (51-504): 2.59e-59: 202: 39.83
+	Hs
		125067 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		314017 BAG4_HUMAN (381-499): 3.45e-33: 134: 43.70		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Hs
		809011 BAG5_HUMAN (418-498): 3.23e-17: 86.4: 41.98		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00