HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: WWC2 (Q6AWC2)
Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)
Gene: WWC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24682284
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1192
+	Hs
		325937 LATS1_HUMAN (1-1130): 0: 934: 100.00		WWC3_HUMAN (6-1192): 0: 836: 43.32
+	Hs
		1149656 LATS2_HUMAN (13-1121): 0: 751: 49.61		WWC2_HUMAN (1-1192): 0: 1008: 100.00
+	Hs
		325797 LATS1_HUMAN (1-1130): 0: 934: 100.00		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Hs
		1344970 LATS2_HUMAN (13-1121): 0: 751: 49.61		WWC3_HUMAN (6-1192): 0: 836: 43.32
+	Hs
		1220087 LATS2_HUMAN (13-1121): 0: 751: 49.61		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Hs
		325859 LATS1_HUMAN (1-1130): 0: 934: 100.00		MAGI1_HUMAN (1-300): 2.32e-62: 236: 18.94
+	Hs
		325914 LATS1_HUMAN (1-1130): 0: 934: 100.00		WWOX_HUMAN (5-198): 5.51e-47: 176: 21.11
+	Hs
		325886 LATS1_HUMAN (1-1130): 0: 934: 100.00		WWP1_HUMAN (6-136): 2.07e-35: 148: 23.78
+	Hs
		325772 LATS1_HUMAN (1-1130): 0: 934: 100.00		MAGI3_HUMAN (9-97): 1.18e-34: 146: 43.82
+	Hs
		325853 LATS1_HUMAN (1-1130): 0: 934: 100.00		ITCH_HUMAN (7-143): 1.17e-33: 142: 24.66
+	Hs
		125071 LATS1_HUMAN (1-1130): 0: 934: 100.00		WWP2_HUMAN (3-143): 4.17e-30: 131: 23.84
+	Hs
		325888 LATS1_HUMAN (1-1130): 0: 934: 100.00		SAV1_HUMAN (4-88): 3.52e-27: 117: 38.82
+	Hs
		325894 LATS1_HUMAN (1-1130): 0: 934: 100.00		SMUF2_HUMAN (9-163): 1.79e-22: 106: 15.61
+	Hs
		325898 LATS1_HUMAN (1-1130): 0: 934: 100.00		SMUF1_HUMAN (40-194): 1.56e-14: 80.8: 16.49
+	Hs
		325655 LATS1_HUMAN (1-1130): 0: 934: 100.00		NEDD4_HUMAN (1-173): 9.35e-12: 71.9: 15.64
+	Hs
		325656 LATS1_HUMAN (1-1130): 0: 934: 100.00		YAP1_HUMAN (41-163): 9.64e-10: 64.5: 18.25
+	Hs
		1300675 LATS2_HUMAN (13-1121): 0: 751: 49.61		MAGI1_HUMAN (1-300): 2.32e-62: 236: 18.94
+	Hs
		1330812 LATS2_HUMAN (13-1121): 0: 751: 49.61		SAV1_HUMAN (4-88): 3.52e-27: 117: 38.82
+	Hs
		808286 LATS2_HUMAN (13-1121): 0: 751: 49.61		NEDD4_HUMAN (1-173): 9.35e-12: 71.9: 15.64
+	Hs
		808960 LATS2_HUMAN (13-1121): 0: 751: 49.61		YAP1_HUMAN (41-163): 9.64e-10: 64.5: 18.25