HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.80	0.751

Property	Details
Experiments	30833792, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 276
+	Hs
		328656 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		STX1B_HUMAN (4-273): 3.81e-67: 212: 23.19
+	Hs
		328672 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		STX1A_HUMAN (17-273): 6.84e-67: 211: 23.19
+	Hs
		328635 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		STX2_HUMAN (16-272): 3.4e-66: 209: 26.62
+	Dm
		1174524 Q7JYX5_DROME (4-96): 8e-33: 115: 31.18		STX1A_DROME (4-273): 6.42e-64: 204: 22.10
+	At
		1020603 VA713_ARATH (4-91): 1.92e-32: 114: 22.73		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	Hs
		160855 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		STX16_HUMAN (6-250): 1.61e-56: 186: 25.00
+	At
		1020601 VA714_ARATH (4-95): 2.98e-31: 111: 23.66		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	At
		1020624 VA721_ARATH (5-92): 6.51e-31: 110: 26.14		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	Hs
		189356 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	At
		265751 VA721_ARATH (5-92): 6.51e-31: 110: 26.14		SYP41_ARATH (2-273): 4.64e-58: 189: 21.07
+	Hs
		328661 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		STX4_HUMAN (6-272): 1.26e-53: 177: 24.27
+	Hs
		328664 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		STX3_HUMAN (5-250): 2.57e-53: 176: 25.20
+	Dm
		1263439 Q7JYX5_DROME (4-96): 8e-33: 115: 31.18		Q7K0X9_DROME (21-274): 3.76e-54: 178: 31.84
+	At
		1457166 VA721_ARATH (5-92): 6.51e-31: 110: 26.14		SYP43_ARATH (2-273): 2.12e-55: 183: 20.00
+	Hs
		328768 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		X5D7S1_HUMAN (17-272): 5.06e-53: 174: 21.01
+	Hs
		72904 VAMP5_HUMAN (1-116): 6.16e-35: 118: 100.00		B1AJQ6_HUMAN (1-192): 1.14e-50: 167: 88.84
+	At
		1192502 VA721_ARATH (5-92): 6.51e-31: 110: 26.14		SY111_ARATH (4-252): 1.65e-51: 172: 19.77
+	Dm
		1263472 Q7JYX5_DROME (4-96): 8e-33: 115: 31.18		Q9VU45_DROME (13-269): 2.96e-49: 166: 28.41
+	Dm
		1263468 Q7JYX5_DROME (4-96): 8e-33: 115: 31.18		Q9VR90_DROME (166-256): 7.1e-11: 63.5: 36.26
+	At
		1355121 VA721_ARATH (5-92): 6.51e-31: 110: 26.14		SY132_ARATH (107-252): 5.36e-12: 66.6: 32.88