HitPredict

Interactor 1: OXSR1 (O95747)
Serine/threonine-protein kinase OSR1 (EC 2.7.11.1) (Oxidative stress-responsive 1 protein)
Gene: OXSR1

Interactor 2: DEFI8 (Q6ZN54)
Differentially expressed in FDCP 8 homolog (DEF-8)
Gene: DEF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1_1~Pkinase
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 527 Hs			1 512
+	Dm
		1345436 HIPPO_DROME (17-346): 8.03e-56: 200: 36.80		DEFI8_DROME (140-504): 2.49e-131: 392: 36.10
+	Hs
		436752 STK39_HUMAN (10-527): 1.84e-153: 451: 73.75		KPCB_HUMAN (151-269): 6.32e-21: 98.3: 15.00
+	Hs
		1035003 MARK2_HUMAN (3-517): 9.8e-128: 393: 18.68		KPCE_HUMAN (151-250): 8.1e-23: 104: 17.43
+	Mm
		591006 AKT1_MOUSE (1-359): 5.93e-128: 383: 21.47		KPCE_MOUSE (151-250): 4.13e-23: 105: 18.35
+	Hs
		728188 AKT1_HUMAN (1-359): 1.06e-127: 383: 21.47		KPCD_HUMAN (153-250): 5.88e-21: 98.6: 17.93
+	Hs
		436615 AKT1_HUMAN (1-359): 1.06e-127: 383: 21.47		KPCB_HUMAN (151-269): 6.32e-21: 98.3: 15.00
+	Hs
		692048 MARK3_HUMAN (5-516): 5.03e-131: 400: 18.40		KPCT_HUMAN (201-250): 1.39e-14: 78.6: 24.00
+	Hs
		728184 AKT1_HUMAN (1-359): 1.06e-127: 383: 21.47		KPCT_HUMAN (201-250): 1.39e-14: 78.6: 24.00
+	Hs
		1034994 KS6A2_HUMAN (15-339): 4.47e-93: 301: 23.72		KPCE_HUMAN (151-250): 8.1e-23: 104: 17.43
+	Hs
		603275 KS6A2_HUMAN (15-339): 4.47e-93: 301: 23.72		KPCA_HUMAN (151-250): 2.81e-20: 96.3: 16.83
+	Hs
		1048289 M4K3_HUMAN (14-290): 7.1e-55: 200: 42.35		KPCT_HUMAN (201-250): 1.39e-14: 78.6: 24.00
+	Mm
		1034942 M4K3_MOUSE (14-290): 5.11e-54: 197: 41.28		KPCT_MOUSE (201-250): 1.02e-14: 79: 24.00