HitPredict

Interactor 1: CYTC (P01034)
Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin)
Gene: CST3

Interactor 2: CYTC (P01034)
Cystatin-C (Cystatin-3) (Gamma-trace) (Neuroendocrine basic polypeptide) (Post-gamma-globulin)
Gene: CST3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 25479090, 26865059
Identification Methods x-ray crystallography, electron microscopy, light microscopy, infrared spectroscopy, classical fluorescence spectroscopy, transmission electron microscopy, dynamic light scattering
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cystatin~Cystatin
Common GO terms GO:0001540 - amyloid-beta binding
GO:0002020 - protease binding
GO:0004866 - endopeptidase inhibitor activity
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
and 20 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 146
Hs

1 146
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024