HitPredict

Interactor 1: NECP1 (P69682)
Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1)
Gene: Necap1

Interactor 2: Q66HM2 (Q66HM2)
AP-2 complex subunit alpha
Gene: Ap2a2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	17762867
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~DUF1681
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 277 Rn			1 939
+	Mm
		604493 NECP1_MOUSE (1-277): 8.79e-163: 454: 97.11		AP2A2_MOUSE (1-939): 0: 902: 99.57
+	Hs
		323758 NECP1_HUMAN (1-277): 7.97e-164: 456: 92.42		AP2A2_HUMAN (1-939): 0: 881: 95.85
+	Hs
		344748 NECP1_HUMAN (1-277): 7.97e-164: 456: 92.42		AP2A1_HUMAN (1-939): 0: 864: 78.47
+	Rn
		93083 NECP1_RAT (1-277): 2.29e-158: 443: 100.00		D3ZUY8_RAT (1-939): 0: 859: 81.15
+	Hs
		323791 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP2A2_HUMAN (1-939): 0: 881: 95.85
+	Hs
		344811 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP2A1_HUMAN (1-939): 0: 864: 78.47
+	Hs
		989054 NECP1_HUMAN (1-277): 7.97e-164: 456: 92.42		AP2B1_HUMAN (36-934): 0: 622: 16.79
+	Hs
		225837 NECP1_HUMAN (1-277): 7.97e-164: 456: 92.42		AP1G1_HUMAN (1-824): 0: 602: 24.91
+	Hs
		1083280 NECP1_HUMAN (1-277): 7.97e-164: 456: 92.42		AP1B1_HUMAN (36-934): 0: 601: 17.21
+	Hs
		989137 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP2B1_HUMAN (36-934): 0: 622: 16.79
+	Hs
		225856 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP1G1_HUMAN (1-824): 0: 602: 24.91
+	Hs
		1083323 NECP2_HUMAN (4-277): 1.13e-143: 405: 61.51		AP1B1_HUMAN (36-934): 0: 601: 17.21