Protein: NECP1
Adaptin ear-binding coat-associated protein 1 (NECAP endocytosis-associated protein 1) (NECAP-1)

Gene: NECP1, NECAP1
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q8NC96

Gene Ontology (top 5):
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005905 - clathrin-coated pit
GO:0015031 - protein transport
GO:0016192 - vesicle-mediated transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1335268

AP2M1
AP-2 complex subunit mu

5

4

High-throughput

0.932

High

1083280

AP1B1
AP-1 complex subunit beta-1

2

12

High-throughput

0.783

High

225837

AP1G1
AP-1 complex subunit gamma-1

2

12

Small-scale

0.754

High

323758

AP2A2
AP-2 complex subunit alpha-2

1

12

High-throughput

0.691

High

344748

AP2A1
AP-2 complex subunit alpha-1

1

12

High-throughput

0.691

High

989054

AP2B1
AP-2 complex subunit beta

1

12

High-throughput

0.691

High

1335271

AP1M1
AP-1 complex subunit mu-1

1

4

High-throughput

0.691

High

1335274

NECP2
Adaptin ear-binding coat-associated protein 2

3

0

High-throughput

0.638

High

1335279

AP1M2
AP-1 complex subunit mu-2

1

4

High-throughput

0.618

High

920482

DAPK1
Death-associated protein kinase 1

1

1

High-throughput

0.536

High

487541

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.536

High

922595

AP2S1
AP-2 complex subunit sigma

1

6

High-throughput

0.536

High

987121

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.536

High

1039536

TOP2B
DNA topoisomerase 2-beta

1

1

High-throughput

0.536

High

1115824

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

1

High-throughput

0.536

High

1217161

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.536

High

1323941

H2B3B
Histone H2B type 3-B

1

1

High-throughput

0.536

High

332016

KAT7
Histone acetyltransferase KAT7

1

0

High-throughput

0.513

High

538992

EPB41
Protein 4.1

1

0

High-throughput

0.513

High

892900

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.513

High

956222

RAB4B
Ras-related protein Rab-4B

1

0

High-throughput

0.513

High

1026136

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1132620

KIF22
Kinesin-like protein KIF22

1

0

High-throughput

0.513

High

1134647

NUMA1
Nuclear mitotic apparatus protein 1

1

0

High-throughput

0.513

High

1335264

CATIN
Splicing factor Cactin

1

0

High-throughput

0.513

High

1335275

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

422625

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

243682

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

1

High-throughput

0.489

High

277750

H2AY
Core histone macro-H2A.1

1

3

High-throughput

0.489

High

502059

H2AZ
Histone H2A.Z

1

2

High-throughput

0.489

High

542582

TOP2A
DNA topoisomerase 2-alpha

1

1

High-throughput

0.489

High

595825

H13
Histone H1.3

1

1

High-throughput

0.489

High

596242

H12
Histone H1.2

1

1

High-throughput

0.489

High

703352

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

1

High-throughput

0.489

High

1219192

SPAT1
Spermatogenesis-associated protein 1

1

1

High-throughput

0.489

High

1232697

H2A2A
Histone H2A type 2-A

1

1

High-throughput

0.489

High

1335269

H2A1J
Histone H2A type 1-J

1

1

High-throughput

0.489

High

1335276

H2AW
Core histone macro-H2A.2

1

3

High-throughput

0.489

High

1335277

BAZ1B
Tyrosine-protein kinase BAZ1B

1

1

High-throughput

0.489

High

791546

SYUA
Alpha-synuclein

1

1

High-throughput

0.481

High

1048919

REL
Proto-oncogene c-Rel

1

1

High-throughput

0.481

High

1335272

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.480

High

159754

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

1

High-throughput

0.479

High

346081

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

839801

EPS15
Epidermal growth factor receptor substrate 15

1

5

High-throughput

0.479

High

942755

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

4

High-throughput

0.479

High

946840

H2B1D
Histone H2B type 1-D

1

1

High-throughput

0.479

High

986576

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

1213070

RHG21
Rho GTPase-activating protein 21

1

1

High-throughput

0.479

High

620481

NUCL
Nucleolin

1

0

High-throughput

0.458

High

530093

TAU
Microtubule-associated protein tau

1

3

High-throughput

0.445

High

1234864

PKHA7
Pleckstrin homology domain-containing family A member 7

1

1

High-throughput

0.445

High

1206323

Q5JSD8
Rho GTPase activating protein 21

1

1

High-throughput

0.407

High

355562

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

High-throughput

0.279

Low

455827

H10
Histone H1.0

1

0

High-throughput

0.279

Low

755755

MCM4
DNA replication licensing factor MCM4

1

0

High-throughput

0.279

Low

980002

H4
Histone H4

1

0

High-throughput

0.279

Low

1097431

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.279

Low

1129654

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.279

Low

1137396

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.279

Low

1258881

H32
Histone H3.2

1

0

High-throughput

0.279

Low

1335265

PHIP
PH-interacting protein

1

0

High-throughput

0.279

Low

1335266

H1X
Histone H1.10

1

0

High-throughput

0.279

Low

1335267

RAD50
DNA repair protein RAD50

1

0

High-throughput

0.279

Low

1335270

TMUB1
Transmembrane and ubiquitin-like domain-containing protein 1

1

0

High-throughput

0.279

Low

1335273

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.279

Low

315784

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.249

Low

1335278

TRI17
E3 ubiquitin-protein ligase TRIM17

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025