HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 36424410
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 586
+	Hs
		345637 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82
+	Hs
		345816 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74
+	Hs
		345660 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85
+	Hs
		345638 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		346579 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22
+	Hs
		359449 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C6A_HUMAN (4-407): 1.22e-124: 380: 22.82
+	Hs
		378970 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74
+	Hs
		347231 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		K2C73_HUMAN (2-391): 1.07e-53: 193: 19.70
+	Hs
		345739 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		346138 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		PERI_HUMAN (28-390): 1.66e-25: 111: 30.79
+	Hs
		379010 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Hs
		359555 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		595120 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Hs
		359716 SRBP1_HUMAN (95-453): 2.54e-33: 135: 16.19		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		378927 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		378972 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Hs
		379091 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		PERI_HUMAN (28-390): 1.66e-25: 111: 30.79