HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: UBP36 (Q9P275)
Ubiquitin carboxyl-terminal hydrolase 36 (EC 2.3.2.-) (EC 3.4.19.12) (Deubiquitinating enzyme 36) (Ubiquitin thioesterase 36) (Ubiquitin-specific-processing protease 36)
Gene: USP36

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	25775507, 29467282, 36424410, 21150319
Identification Methods	enzymatic study, affinity chromatography technology, pull down, proximity labelling technology, tandem affinity purification
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 1123
+	Hs
		379972 MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40		UBP36_HUMAN (1-1123): 0: 646: 100.00
+	Hs
		348252 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP22_HUMAN (109-427): 7.21e-113: 362: 25.62
+	Hs
		347922 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP42_HUMAN (1-1023): 1.74e-104: 359: 31.00
+	Hs
		64198 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP27_HUMAN (109-440): 9.55e-109: 349: 24.53
+	Hs
		347132 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP34_HUMAN (8-456): 3.65e-95: 337: 19.51
+	Hs
		271012 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP2_HUMAN (8-428): 1.38e-97: 324: 26.14
+	Hs
		348388 MYC_HUMAN (1-454): 1.73e-122: 366: 100.00		UBP3_HUMAN (75-431): 1.55e-96: 319: 25.61
+	Dm
		1373210 MYC_DROME (210-454): 3.25e-30: 126: 26.74		UBP36_DROME (639-1107): 1.54e-33: 142: 13.21