HitPredict

Interactor 1: DCTN1 (Q14203)
Dynactin subunit 1 (150 kDa dynein-associated polypeptide) (DAP-150) (DP-150) (p135) (p150-glued)
Gene: DCTN1

Interactor 2: DYHC1 (Q14204)
Cytoplasmic dynein 1 heavy chain 1 (Cytoplasmic dynein heavy chain 1) (Dynein heavy chain, cytosolic)
Gene: DYNC1H1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.730

The method score is based on:

Property Details
Experiments 26638075, 14600259, 34079125, 26496610, 35271311, 22956769
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005874 - microtubule
GO:0005938 - cell cortex
GO:0007097 - nuclear migration
and 5 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1278
Hs

1 4646
+ Dm
+ Hs
+ Mm
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024