HitPredict

Interactor 1: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Interactor 2: MPP7 (Q5T2T1)
MAGUK p55 subfamily member 7
Gene: MPP7

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	30194290, 34591642
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 576
+	Hs
		350231 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		1070233 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		349383 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		914120 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		MPP7_HUMAN (1-576): 5.36e-166: 486: 100.00
+	Hs
		350623 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PALS2_HUMAN (14-575): 3.59e-142: 424: 34.21
+	Hs
		159130 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33
+	Hs
		159212 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		CSKP_HUMAN (1-575): 8.86e-131: 406: 30.33
+	Hs
		350339 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		PALS1_HUMAN (28-574): 1.04e-123: 380: 37.70
+	Hs
		1070296 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		PALS1_HUMAN (28-574): 1.04e-123: 380: 37.70
+	Hs
		349476 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		PALS1_HUMAN (28-574): 1.04e-123: 380: 37.70
+	Hs
		350077 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		EM55_HUMAN (78-575): 3.3e-116: 354: 31.28
+	Hs
		348614 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		EM55_HUMAN (78-575): 3.3e-116: 354: 31.28
+	Hs
		349246 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		EM55_HUMAN (78-575): 3.3e-116: 354: 31.28
+	Hs
		350124 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		1021495 RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		348639 RASN_HUMAN (1-189): 9.9e-80: 236: 100.00		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		349277 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		350420 RASK_HUMAN (16-189): 7.56e-85: 249: 85.71		DLG3_HUMAN (139-485): 4.74e-17: 87: 10.74
+	Hs
		914039 RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88		DLG1_HUMAN (2-228): 9.88e-24: 108: 16.33
+	Hs
		349543 RASH_HUMAN (1-188): 8.6e-78: 232: 85.64		DLG3_HUMAN (139-485): 4.74e-17: 87: 10.74