HitPredict

Interactor 1: FBLN4 (O95967)
EGF-containing fibulin-like extracellular matrix protein 2 (Fibulin-4) (FIBL-4) (Protein UPH1)
Gene: EFEMP2

Interactor 2: ELN (P15502)
Elastin (Tropoelastin)
Gene: ELN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	19570982
Identification Methods	surface plasmon resonance, enzyme linked immunosorbent assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005201 - extracellular matrix structural constituent GO:0005576 - extracellular region GO:0031012 - extracellular matrix GO:0071953 - elastic fiber
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 443 Hs			1 786
+	Hs
		584620 FBLN2_HUMAN (8-377): 4.79e-35: 140: 25.94		ELN_HUMAN (1-786): 3.25e-43: 170: 100.00
+	Hs
		584622 NID2_HUMAN (8-292): 1.33e-29: 124: 18.58		ELN_HUMAN (1-786): 3.25e-43: 170: 100.00
+	Hs
		584613 FBLN1_HUMAN (118-347): 4.14e-19: 92.2: 26.80		ELN_HUMAN (1-786): 3.25e-43: 170: 100.00
+	Hs
		584626 FBLN5_HUMAN (7-250): 1.47e-11: 67.9: 25.94		ELN_HUMAN (1-786): 3.25e-43: 170: 100.00
+	Hs
		584617 FBN1_HUMAN (34-231): 8.33e-11: 66.6: 23.08		ELN_HUMAN (1-786): 3.25e-43: 170: 100.00
+	Hs
		584618 FBN2_HUMAN (34-231): 4.88e-10: 64.3: 22.98		ELN_HUMAN (1-786): 3.25e-43: 170: 100.00
+	Hs
		384314 NID2_HUMAN (8-292): 1.33e-29: 124: 18.58		CO4A1_HUMAN (300-785): 1.09e-21: 103: 16.97
+	Hs
		384152 NID2_HUMAN (8-292): 1.33e-29: 124: 18.58		CO1A1_HUMAN (1-458): 2.47e-20: 99.1: 17.73
+	Dm
		119684 CUBN_DROME (4-238): 3.55e-29: 123: 17.77		M9PB30_DROME (206-645): 2.57e-15: 83.1: 14.29
+	Hs
		132971 MATN2_HUMAN (238-403): 1.81e-10: 65.2: 18.02		CO1A1_HUMAN (1-458): 2.47e-20: 99.1: 17.73
+	Hs
		635444 TENA_HUMAN (236-423): 9.25e-10: 63.3: 7.98		CO5A1_HUMAN (381-786): 5.19e-12: 72.1: 15.53