Interactor 1: ERCC3 (P19447)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB (TFIIH subunit XPB) (EC 5.6.2.4) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA 3'-5' helicase/translocase XPB) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
Gene: ERCC3
Interactor 2: TF2H4 (Q92759)
General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit)
Gene: GTF2H4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.971 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26340423, 33961781, 36041630, 28514442, 15220921, 9118947, 24981860, 33453189, 19172752 |
| Identification Methods | pull down, affinity chromatography technology, biochemical, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ERCC3_RAD25_C~Tfb2, ERCC3_RAD25_C~Tfb2_C, Helicase_C_3~Tfb2 |
| Common GO terms | GO:0000439 - transcription factor TFIIH core complex GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex GO:0005675 - transcription factor TFIIH holo complex and 3 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
