HitPredict

Interactor 1: PAK4 (O96013)
Serine/threonine-protein kinase PAK 4 (EC 2.7.11.1) (p21-activated kinase 4) (PAK-4)
Gene: PAK4

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005912 - adherens junction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 591 Hs			1 1356
+	Hs
		1148365 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		PAR3L_HUMAN (1-1353): 6.79e-109: 374: 33.38
+	Mm
		1190517 PAK6_MOUSE (1-591): 2.12e-169: 499: 45.66		DLG4_MOUSE (540-699): 7.92e-23: 107: 27.98
+	Hs
		1148349 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		PZRN4_HUMAN (265-1077): 4.47e-67: 249: 14.27
+	Hs
		1348527 PAK6_HUMAN (1-591): 5.36e-170: 500: 45.72		LNX1_HUMAN (73-395): 5.04e-14: 79.3: 13.74
+	Dm
		1268892 PAK_DROME (7-589): 5.46e-157: 468: 34.03		SCRIB_DROME (554-719): 3.84e-13: 76.7: 22.49
+	Hs
		1148355 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		MAGI2_HUMAN (68-1178): 1.7e-38: 159: 13.69
+	Dm
		1268891 Q9VEV1_DROME (2-589): 2.81e-143: 428: 28.74		SCRIB_DROME (554-719): 3.84e-13: 76.7: 22.49
+	Hs
		1148407 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		PZRN3_HUMAN (449-1168): 5.42e-31: 134: 12.79
+	Mm
		1223775 KS6A2_MOUSE (318-591): 5.41e-114: 358: 25.61		DLG4_MOUSE (540-699): 7.92e-23: 107: 27.98
+	Hs
		1006070 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		DLG4_HUMAN (540-699): 1.04e-22: 107: 27.98
+	Hs
		1148381 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		MAGI1_HUMAN (413-780): 3.17e-16: 87: 15.48
+	Hs
		1148364 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		LNX1_HUMAN (73-395): 5.04e-14: 79.3: 13.74
+	Hs
		1148345 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		MAGI3_HUMAN (438-1311): 9.08e-14: 78.9: 11.80
+	Hs
		908111 KS6A3_HUMAN (263-591): 2.97e-114: 358: 24.13		SCRIB_HUMAN (458-668): 1.99e-09: 64.7: 26.96
+	Hs
		1122237 KS6A1_HUMAN (274-583): 3.9e-111: 350: 24.32		SCRIB_HUMAN (458-668): 1.99e-09: 64.7: 26.96
+	Hs
		1090197 STK26_HUMAN (315-574): 2.22e-52: 186: 38.31		PTN13_HUMAN (39-368): 1.89e-16: 87.8: 12.50
+	Hs
		1348555 PAK5_HUMAN (1-323): 1.21e-42: 165: 27.68		LNX1_HUMAN (73-395): 5.04e-14: 79.3: 13.74
+	Hs
		1096430 PAK1_HUMAN (3-188): 1.43e-32: 133: 19.79		SCRIB_HUMAN (458-668): 1.99e-09: 64.7: 26.96
+	Hs
		1097190 PAK2_HUMAN (8-202): 1.98e-27: 118: 15.74		SCRIB_HUMAN (458-668): 1.99e-09: 64.7: 26.96