HitPredict

Interactor 1: KAPCA (P00517)
cAMP-dependent protein kinase catalytic subunit alpha (PKA C-alpha) (EC 2.7.11.11)
Gene: PRKACA

Interactor 2: TAU (P29172)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Bos taurus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	10840038
Identification Methods	protein kinase assay
Interaction Type	phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 351 Bt			1 448
+	Mm
		424696 KAPCA_MOUSE (1-351): 2.02e-163: 462: 97.72		TAU_MOUSE (12-448): 5.59e-58: 205: 68.47
+	Hs
		529026 KAPCA_HUMAN (1-351): 5.65e-165: 466: 99.43		TAU_HUMAN (5-448): 1.49e-52: 190: 65.78
+	Hs
		529085 KAPCB_HUMAN (1-351): 3.61e-163: 461: 92.88		TAU_HUMAN (5-448): 1.49e-52: 190: 65.78
+	Rn
		98733 KAPCB_RAT (1-351): 1.75e-160: 454: 92.31		F1LST4_RAT (10-447): 1.45e-54: 196: 67.56
+	Rn
		620042 KAPCB_RAT (1-351): 1.75e-160: 454: 92.31		TAU_RAT (10-448): 1.7e-54: 195: 67.41
+	Hs
		529083 KAPCG_HUMAN (1-351): 2.97e-161: 456: 83.19		TAU_HUMAN (5-448): 1.49e-52: 190: 65.78
+	Hs
		529186 AKT2_HUMAN (18-347): 2.78e-148: 428: 37.73		TAU_HUMAN (5-448): 1.49e-52: 190: 65.78
+	Hs
		529185 AKT1_HUMAN (4-347): 1.64e-146: 424: 38.92		TAU_HUMAN (5-448): 1.49e-52: 190: 65.78
+	Hs
		536312 KAPCA_HUMAN (1-351): 5.65e-165: 466: 99.43		MTAP2_HUMAN (18-448): 3.92e-37: 147: 31.71
+	Hs
		536315 KAPCB_HUMAN (1-351): 3.61e-163: 461: 92.88		MTAP2_HUMAN (18-448): 3.92e-37: 147: 31.71
+	Hs
		536314 KAPCG_HUMAN (1-351): 2.97e-161: 456: 83.19		MTAP2_HUMAN (18-448): 3.92e-37: 147: 31.71
+	Hs
		529095 KS6B1_HUMAN (23-351): 1.89e-139: 407: 35.38		TAU_HUMAN (5-448): 1.49e-52: 190: 65.78
+	Hs
		122907 SGK1_HUMAN (34-342): 8.17e-85: 265: 42.22		TAU_HUMAN (5-448): 1.49e-52: 190: 65.78