HitPredict

Interactor 1: VTDB (P02774)
Vitamin D-binding protein (DBP) (VDB) (Gc protein-derived macrophage activating factor) (Gc-MAF) (GcMAF) (Gc-globulin) (Group-specific component) (Gc) (Vitamin D-binding protein-macrophage activating factor) (DBP-maf)
Gene: GC

Interactor 2: POTEI (P0CG38)
POTE ankyrin domain family member I
Gene: POTEI

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Serum_albumin, Actin~VitD-bind_III
Common GO terms	GO:0005615 - extracellular space GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 474 Hs			1 1075
+	Hs
		60271 VTDB_HUMAN (1-474): 0: 556: 100.00		POTEF_HUMAN (1-1074): 0: 1077: 96.83
+	Hs
		364025 VTDB_HUMAN (1-474): 0: 556: 100.00		ACTBM_HUMAN (701-1075): 0: 754: 94.93
+	Hs
		474797 AFAM_HUMAN (10-392): 1.99e-32: 132: 20.40		POTEI_HUMAN (1-1075): 0: 1088: 100.00
+	Hs
		364001 VTDB_HUMAN (1-474): 0: 556: 100.00		ACTB_HUMAN (701-1075): 0: 577: 91.20
+	Hs
		364002 VTDB_HUMAN (1-474): 0: 556: 100.00		ACTA_HUMAN (699-1075): 0: 572: 85.94
+	Hs
		364005 VTDB_HUMAN (1-474): 0: 556: 100.00		ACTS_HUMAN (699-1075): 0: 571: 85.68
+	Hs
		798406 AFAM_HUMAN (10-392): 1.99e-32: 132: 20.40		ACTA_HUMAN (699-1075): 0: 572: 85.94