HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33731348
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 282
+	Hs
		369739 ESR1_HUMAN (1-595): 0: 599: 100.00		PAP1L_HUMAN (1-272): 4.36e-38: 143: 14.59
+	Hs
		368886 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		369534 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		370422 ESR1_HUMAN (1-595): 0: 599: 100.00		PABP3_HUMAN (1-267): 3.29e-34: 132: 13.77
+	Hs
		369421 ESR1_HUMAN (1-595): 0: 599: 100.00		TIAR_HUMAN (113-209): 9.67e-20: 89.4: 20.62
+	Hs
		369064 ESR1_HUMAN (1-595): 0: 599: 100.00		TIA1_HUMAN (114-207): 1.64e-18: 86.4: 21.28
+	Hs
		369577 ESR1_HUMAN (1-595): 0: 599: 100.00		CIRBP_HUMAN (121-193): 2.19e-10: 60.1: 58.90
+	Hs
		1040373 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		1119140 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PAP1L_HUMAN (1-272): 4.36e-38: 143: 14.59
+	Hs
		1031409 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		1269600 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		PABP3_HUMAN (1-267): 3.29e-34: 132: 13.77
+	Hs
		925088 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TRA2B_HUMAN (1-279): 2.66e-34: 127: 52.30
+	Hs
		377309 GCR_HUMAN (5-557): 4.67e-109: 346: 22.51		TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00
+	Hs
		782537 HNF4A_HUMAN (146-592): 2.13e-118: 361: 20.58		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		963552 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TIAR_HUMAN (113-209): 9.67e-20: 89.4: 20.62
+	Hs
		680471 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		TIA1_HUMAN (114-207): 1.64e-18: 86.4: 21.28
+	Hs
		516359 NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54		PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77
+	Hs
		611434 NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54		PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13
+	Hs
		1047895 ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88		CIRBP_HUMAN (121-193): 2.19e-10: 60.1: 58.90
+	Mm
		509289 RARA_MOUSE (81-545): 8.36e-104: 323: 22.37		PABP1_MOUSE (1-267): 1.23e-37: 142: 13.77