HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: LIS1 (P43034)
Platelet-activating factor acetylhydrolase IB subunit beta (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha)
Gene: PAFAH1B1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29467282
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 410
+	Hs
		371688 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		GBB2_HUMAN (166-410): 4.44e-51: 176: 20.48
+	Hs
		222414 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PLRG1_HUMAN (224-409): 2.03e-43: 160: 24.73
+	Hs
		373290 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		NLE1_HUMAN (1-219): 1.04e-43: 160: 22.51
+	Mm
		373704 MYC_MOUSE (1-454): 1.16e-117: 353: 89.01		FBXW7_MOUSE (1-257): 6.4e-43: 161: 20.68
+	Hs
		372801 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SNR40_HUMAN (328-408): 1.04e-17: 85.6: 26.83
+	Hs
		372767 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		FBXW7_HUMAN (323-408): 1.31e-15: 81: 33.33
+	Hs
		371712 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		RACK1_HUMAN (103-261): 2.67e-16: 80.9: 33.13
+	Hs
		209181 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		PRP4_HUMAN (324-409): 2.78e-13: 73.3: 15.96
+	Hs
		371643 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		WDR5_HUMAN (15-138): 8.08e-11: 64.8: 15.63
+	Dm
		1489024 MYC_DROME (210-454): 1.35e-29: 124: 26.74		FBXW7_DROME (50-403): 1.17e-74: 254: 27.52
+	Hs
		222417 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		PLRG1_HUMAN (224-409): 2.03e-43: 160: 24.73
+	Mm
		1189859 SRBP2_MOUSE (124-446): 1.15e-36: 145: 13.60		FBXW7_MOUSE (1-257): 6.4e-43: 161: 20.68
+	Mm
		1353851 SRBP1_MOUSE (172-453): 7.23e-35: 140: 16.61		FBXW7_MOUSE (1-257): 6.4e-43: 161: 20.68
+	Hs
		406479 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		SNR40_HUMAN (328-408): 1.04e-17: 85.6: 26.83
+	Hs
		406466 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		FBXW7_HUMAN (323-408): 1.31e-15: 81: 33.33
+	Hs
		406033 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		RACK1_HUMAN (103-261): 2.67e-16: 80.9: 33.13
+	Hs
		405975 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		WDR5_HUMAN (15-138): 8.08e-11: 64.8: 15.63
+	Hs
		787890 SRBP1_HUMAN (95-453): 7.2e-33: 134: 16.19		FBXW7_HUMAN (323-408): 1.31e-15: 81: 33.33
+	Hs
		648344 USF1_HUMAN (175-453): 3.38e-39: 145: 18.06		WDR5_HUMAN (15-138): 8.08e-11: 64.8: 15.63
+	Hs
		965076 MGAP_HUMAN (151-449): 2.43e-27: 118: 17.71		WDR5_HUMAN (15-138): 8.08e-11: 64.8: 15.63