HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 357
+	Hs
		373290 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		NLE1_HUMAN (45-357): 5.57e-87: 272: 21.05
+	Hs
		371643 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		WDR5_HUMAN (95-357): 5.86e-83: 256: 25.09
+	Hs
		372767 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		FBXW7_HUMAN (53-216): 2.88e-28: 117: 27.17
+	Mm
		373704 MYC_MOUSE (1-454): 1.16e-117: 353: 89.01		FBXW7_MOUSE (53-216): 1.18e-28: 118: 25.88
+	Hs
		405975 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		WDR5_HUMAN (95-357): 5.86e-83: 256: 25.09
+	Hs
		371397 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		LIS1_HUMAN (278-357): 1.05e-18: 88.5: 21.25
+	Hs
		648344 USF1_HUMAN (175-453): 3.38e-39: 145: 18.06		WDR5_HUMAN (95-357): 5.86e-83: 256: 25.09
+	Hs
		406479 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		SNR40_HUMAN (143-357): 4.86e-57: 191: 19.27
+	Hs
		965076 MGAP_HUMAN (151-449): 2.43e-27: 118: 17.71		WDR5_HUMAN (95-357): 5.86e-83: 256: 25.09
+	Mm
		704106 MAX_MOUSE (354-454): 3.61e-25: 102: 32.67		WDR5_MOUSE (95-357): 5.86e-83: 256: 25.09
+	Hs
		959549 MAX_HUMAN (354-454): 1.4e-24: 101: 32.67		WDR5_HUMAN (95-357): 5.86e-83: 256: 25.09
+	Hs
		406466 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		FBXW7_HUMAN (53-216): 2.88e-28: 117: 27.17
+	Hs
		1310104 MGAP_HUMAN (151-449): 2.43e-27: 118: 17.71		SNR40_HUMAN (143-357): 4.86e-57: 191: 19.27
+	Mm
		1189859 SRBP2_MOUSE (124-446): 1.15e-36: 145: 13.60		FBXW7_MOUSE (53-216): 1.18e-28: 118: 25.88
+	Mm
		1353851 SRBP1_MOUSE (172-453): 7.23e-35: 140: 16.61		FBXW7_MOUSE (53-216): 1.18e-28: 118: 25.88
+	Hs
		269113 MITF_HUMAN (155-450): 1.04e-28: 120: 14.15		A16L1_HUMAN (32-344): 8.5e-35: 136: 29.87
+	Hs
		623627 TFEB_HUMAN (180-450): 2.12e-27: 116: 14.59		A16L1_HUMAN (32-344): 8.5e-35: 136: 29.87
+	Hs
		787890 SRBP1_HUMAN (95-453): 7.2e-33: 134: 16.19		FBXW7_HUMAN (53-216): 2.88e-28: 117: 27.17
+	Hs
		959629 MAX_HUMAN (354-454): 1.4e-24: 101: 32.67		FBXW7_HUMAN (53-216): 2.88e-28: 117: 27.17