HitPredict

Interactor 1: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: TBL2 (Q9Y4P3)
Transducin beta-like protein 2 (WS beta-transducin repeats protein) (WS-betaTRP) (Williams-Beuren syndrome chromosomal region 13 protein)
Gene: TBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21150319
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0071456 - cellular response to hypoxia
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 454 Hs			1 447
+	Hs
		371880 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		TBL3_HUMAN (13-447): 1.82e-58: 206: 13.47
+	Hs
		371397 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		LIS1_HUMAN (3-218): 1.16e-50: 178: 11.86
+	Hs
		372801 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		SNR40_HUMAN (258-447): 4.69e-33: 129: 13.02
+	Hs
		371643 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Mm
		373704 MYC_MOUSE (1-454): 1.16e-117: 353: 89.01		FBXW7_MOUSE (220-425): 6.04e-30: 125: 15.46
+	Hs
		284911 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		TAF5L_HUMAN (76-247): 1.77e-26: 114: 15.76
+	Hs
		371712 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		RACK1_HUMAN (266-445): 5.7e-20: 91.9: 16.30
+	Hs
		373290 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		NLE1_HUMAN (356-445): 3.96e-18: 88.3: 15.56
+	Hs
		302728 MYC_HUMAN (1-454): 4.53e-121: 362: 100.00		CIAO1_HUMAN (81-215): 3.82e-16: 81.1: 18.12
+	Hs
		406479 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		SNR40_HUMAN (258-447): 4.69e-33: 129: 13.02
+	Hs
		405975 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Hs
		406033 MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40		RACK1_HUMAN (266-445): 5.7e-20: 91.9: 16.30
+	Mm
		1189859 SRBP2_MOUSE (124-446): 1.15e-36: 145: 13.60		FBXW7_MOUSE (220-425): 6.04e-30: 125: 15.46
+	Hs
		648344 USF1_HUMAN (175-453): 3.38e-39: 145: 18.06		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Mm
		1353851 SRBP1_MOUSE (172-453): 7.23e-35: 140: 16.61		FBXW7_MOUSE (220-425): 6.04e-30: 125: 15.46
+	Hs
		284921 MYCL_HUMAN (29-449): 4.23e-41: 151: 30.94		TAF5L_HUMAN (76-247): 1.77e-26: 114: 15.76
+	Hs
		1310104 MGAP_HUMAN (151-449): 2.43e-27: 118: 17.71		SNR40_HUMAN (258-447): 4.69e-33: 129: 13.02
+	Hs
		965076 MGAP_HUMAN (151-449): 2.43e-27: 118: 17.71		WDR5_HUMAN (4-165): 9.61e-31: 122: 8.93
+	Mm
		704106 MAX_MOUSE (354-454): 3.61e-25: 102: 32.67		WDR5_MOUSE (4-165): 9.61e-31: 122: 8.93
+	At
		200969 MYC2_ARATH (200-454): 8.3e-32: 130: 18.05		GBLPA_ARATH (76-217): 7.86e-12: 68: 15.79