HitPredict

Interactor 1: RASH (P01112)
GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Gene: HRAS

Interactor 2: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	30442766, 30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 538
+	Hs
		374107 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		NECT2_HUMAN (1-538): 2.84e-91: 291: 100.00
+	Hs
		375796 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		NECT2_HUMAN (1-538): 2.84e-91: 291: 100.00
+	Hs
		976465 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		NECT2_HUMAN (1-538): 2.84e-91: 291: 100.00
+	Hs
		375909 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		CADM1_HUMAN (40-348): 8.18e-67: 224: 20.25
+	Hs
		373936 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		NECT1_HUMAN (19-466): 7.36e-57: 200: 28.66
+	Hs
		374318 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		ROBO1_HUMAN (37-532): 4.85e-54: 199: 12.60
+	Hs
		375536 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		NECT1_HUMAN (19-466): 7.36e-57: 200: 28.66
+	Hs
		376163 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		ROBO1_HUMAN (37-532): 4.85e-54: 199: 12.60
+	Hs
		374217 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		NECT3_HUMAN (30-510): 3.44e-52: 188: 20.54
+	Hs
		375987 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		NECT3_HUMAN (30-510): 3.44e-52: 188: 20.54
+	Hs
		580746 RAB13_HUMAN (4-181): 1.29e-75: 227: 35.14		PVR_HUMAN (25-423): 4.78e-59: 203: 43.92
+	Hs
		374138 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		KIRR1_HUMAN (33-363): 7.42e-16: 82.9: 16.72
+	Hs
		373908 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		PTK7_HUMAN (263-483): 1.84e-13: 75.5: 15.45
+	Hs
		375842 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		KIRR1_HUMAN (33-363): 7.42e-16: 82.9: 16.72
+	Hs
		374079 RASN_HUMAN (1-188): 4.47e-88: 257: 85.64		CADM4_HUMAN (267-538): 2.28e-12: 70.9: 11.38
+	Hs
		375481 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		PTK7_HUMAN (263-483): 1.84e-13: 75.5: 15.45
+	Hs
		375974 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		ROBO2_HUMAN (449-538): 3.83e-09: 61.7: 15.15
+	Hs
		375784 RASK_HUMAN (1-188): 1.61e-84: 249: 86.24		TITIN_HUMAN (171-460): 8.42e-09: 60.9: 13.68
+	Hs
		976484 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		KIRR1_HUMAN (33-363): 7.42e-16: 82.9: 16.72
+	Hs
		976456 RB11A_HUMAN (4-178): 6.31e-73: 220: 33.90		TITIN_HUMAN (171-460): 8.42e-09: 60.9: 13.68