HitPredict

Interactor 1: RASK (P01116)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: KRAS

Interactor 2: PKHA6 (Q9Y2H5)
Pleckstrin homology domain-containing family A member 6 (PH domain-containing family A member 6) (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3)
Gene: PLEKHA6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	30639242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 1048
+	Hs
		374939 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		PKHA5_HUMAN (1-1012): 6.39e-102: 347: 28.45
+	Hs
		374202 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		PKHA5_HUMAN (1-1012): 6.39e-102: 347: 28.45
+	Hs
		1145117 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		PKHA5_HUMAN (1-1012): 6.39e-102: 347: 28.45
+	Hs
		375964 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		PKHA5_HUMAN (1-1012): 6.39e-102: 347: 28.45
+	Hs
		1144962 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		PKHA7_HUMAN (1-952): 8.21e-87: 305: 24.40
+	Hs
		375620 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		PKHA7_HUMAN (1-952): 8.21e-87: 305: 24.40
+	Hs
		374903 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		DOCK9_HUMAN (54-730): 1.78e-68: 254: 11.06
+	Hs
		1145093 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		DOCK9_HUMAN (54-730): 1.78e-68: 254: 11.06
+	Hs
		375912 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		DOCK9_HUMAN (54-730): 1.78e-68: 254: 11.06
+	Hs
		374532 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		ANK2_HUMAN (153-1043): 5.19e-51: 199: 11.56
+	Hs
		375583 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		DOC11_HUMAN (49-729): 6.71e-57: 218: 9.31
+	Hs
		374664 RASH_HUMAN (1-188): 8.44e-87: 254: 86.77		RHG21_HUMAN (2-1037): 2.51e-46: 184: 10.10
+	Hs
		375418 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		ANK2_HUMAN (153-1043): 5.19e-51: 199: 11.56
+	Hs
		1144945 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		RHG21_HUMAN (2-1037): 2.51e-46: 184: 10.10
+	Dm
		473607 RAS1_DROME (1-165): 9.67e-88: 257: 85.46		Q7KNQ9_DROME (23-287): 1.09e-39: 162: 20.22
+	Hs
		375594 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		RHG21_HUMAN (2-1037): 2.51e-46: 184: 10.10
+	Hs
		375965 RASK_HUMAN (16-189): 5.35e-78: 232: 100.00		PKHA2_HUMAN (42-315): 5.64e-49: 182: 20.42
+	Hs
		1140280 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		ACAP2_HUMAN (32-406): 1.76e-39: 159: 15.11
+	Hs
		374203 RASN_HUMAN (1-189): 3.16e-85: 251: 85.19		PKHA1_HUMAN (47-259): 5.68e-34: 137: 25.00
+	Hs
		1145118 RAB35_HUMAN (4-187): 1.26e-82: 244: 31.28		PKHA1_HUMAN (47-259): 5.68e-34: 137: 25.00