HitPredict

Interactor 1: K2C1 (P04264)
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene: KRT1

Interactor 2: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25324306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 644 Hs			1 372
+	Hs
		453476 K2C78_HUMAN (119-543): 1.51e-130: 395: 55.09		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		453276 KRT83_HUMAN (79-563): 3.51e-87: 282: 44.47		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		453117 K2C5_HUMAN (1-496): 2.32e-82: 272: 64.32		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		380439 K2C6B_HUMAN (2-512): 5.16e-79: 263: 62.82		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		453213 K2C6C_HUMAN (2-512): 2.69e-78: 261: 62.62		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		453418 K2C79_HUMAN (28-570): 6.02e-78: 259: 56.15		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00
+	Hs
		359456 K2C6A_HUMAN (2-512): 2.12e-75: 253: 62.43		ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00