HitPredict

Interactor 1: H2B (P02283)
Histone H2B
Gene: H2B, His2B;

Interactor 2: PCL (Q24459)
Polycomb protein Pcl (Polycomblike protein)
Gene: PCL

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	17762866
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 123 Dm			1 1043
+	Hs
		755015 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		ASH2L_HUMAN (475-776): 2.47e-55: 205: 14.37
+	Hs
		981156 H2B1C_HUMAN (3-123): 1.52e-48: 153: 81.30		ASH2L_HUMAN (475-776): 2.47e-55: 205: 14.37
+	Hs
		1132877 H2B1H_HUMAN (3-123): 5.3e-49: 154: 81.30		CHD4_HUMAN (409-579): 1.81e-34: 145: 18.08
+	Hs
		754808 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KMT2A_HUMAN (184-601): 1.16e-34: 146: 12.04
+	Hs
		980708 H2B1C_HUMAN (3-123): 1.52e-48: 153: 81.30		KMT2A_HUMAN (184-601): 1.16e-34: 146: 12.04
+	Hs
		754848 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		CHD4_HUMAN (409-579): 1.81e-34: 145: 18.08
+	Hs
		980773 H2B1C_HUMAN (3-123): 1.52e-48: 153: 81.30		CHD4_HUMAN (409-579): 1.81e-34: 145: 18.08
+	Hs
		980946 H2B1C_HUMAN (3-123): 1.52e-48: 153: 81.30		CHD5_HUMAN (414-578): 3.74e-31: 135: 15.98
+	Hs
		1208916 H2B2F_HUMAN (3-123): 3.46e-49: 154: 81.30		PCLO_HUMAN (2-354): 2.04e-10: 67.4: 16.31
+	Hs
		1372356 H2B1H_HUMAN (3-123): 5.3e-49: 154: 81.30		PCLO_HUMAN (2-354): 2.04e-10: 67.4: 16.31
+	Hs
		659962 H2B1O_HUMAN (3-123): 3.31e-49: 154: 82.11		PCLO_HUMAN (2-354): 2.04e-10: 67.4: 16.31
+	Hs
		449810 H2B1J_HUMAN (3-123): 1.27e-48: 153: 81.30		PCLO_HUMAN (2-354): 2.04e-10: 67.4: 16.31
+	Hs
		754883 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		SRCAP_HUMAN (22-354): 2.47e-10: 67.2: 17.22
+	Hs
		980867 H2B1C_HUMAN (3-123): 1.52e-48: 153: 81.30		SRCAP_HUMAN (22-354): 2.47e-10: 67.2: 17.22
+	Hs
		754917 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KMT2C_HUMAN (33-445): 8.01e-10: 65.5: 12.06
+	Hs
		980938 H2B1C_HUMAN (3-123): 1.52e-48: 153: 81.30		KMT2C_HUMAN (33-445): 8.01e-10: 65.5: 12.06
+	Hs
		161419 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		KMT2D_HUMAN (2-408): 2.62e-09: 63.9: 11.33
+	Hs
		1129680 H2B1H_HUMAN (3-123): 5.3e-49: 154: 81.30		MDC1_HUMAN (24-346): 5.72e-09: 62.6: 19.95
+	Hs
		754844 H2B1B_HUMAN (3-123): 1.14e-48: 153: 82.11		MDC1_HUMAN (24-346): 5.72e-09: 62.6: 19.95
+	Hs
		980769 H2B1C_HUMAN (3-123): 1.52e-48: 153: 81.30		MDC1_HUMAN (24-346): 5.72e-09: 62.6: 19.95