HitPredict

Interactor 1: VWF (P04275)
von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)]
Gene: VWF

Interactor 2: VWF (P04275)
von Willebrand factor (vWF) [Cleaved into: von Willebrand antigen 2 (von Willebrand antigen II)]
Gene: VWF

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.933

The method score is based on:

Property Details
Experiments 888800001074, 17895385, 18182488, 18492805, 21857647
Identification Methods affinity chromatography technology, comigration in gel electrophoresis, molecular sieving, light scattering, dynamic light scattering, comigration in sds page, comigration in non denaturing gel electrophoresis, electron microscopy
Interaction Type physical association, direct interaction, covalent binding

The annotation score is based on:

Property Details
Interacting Pfam domains C8~C8, C8~TIL, C8~VWD, TIL~VWA_N2, TIL~VWD, VWA~VWA, VWA_N2~VWD, VWC~VWC, VWD~VWD
Common GO terms GO:0002020 - protease binding
GO:0005178 - integrin binding
GO:0005518 - collagen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
and 16 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024