HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: RSF1 (Q96T23)
Remodeling and spacing factor 1 (Rsf-1) (HBV pX-associated protein 8) (Hepatitis B virus X-associated protein) (p325 subunit of RSF chromatin-remodeling complex)
Gene: RSF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.668

Property	Details
Experiments	29721183, 31694235, 32867128
Identification Methods	affinity chromatography technology, two hybrid, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 1441
+	Hs
		617359 SP100_HUMAN (25-178): 1.23e-34: 131: 87.66		RSF1_HUMAN (13-1441): 1.85e-171: 553: 100.00
+	Hs
		996848 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		RSF1_HUMAN (13-1441): 1.85e-171: 553: 100.00
+	Hs
		1285342 SOX7_HUMAN (65-181): 1.3e-28: 112: 19.66		PF21A_HUMAN (402-1004): 2.24e-67: 243: 15.05
+	Hs
		297535 TOX4_HUMAN (91-163): 1.19e-27: 111: 38.36		PF21A_HUMAN (402-1004): 2.24e-67: 243: 15.05
+	Hs
		449742 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		RIF1_HUMAN (177-1372): 1.34e-36: 154: 9.80
+	Hs
		725110 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		MYH10_HUMAN (277-1341): 9.72e-46: 183: 10.59
+	Hs
		996851 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		UHRF1_HUMAN (654-1274): 9.34e-39: 158: 13.05
+	Hs
		996705 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		RIF1_HUMAN (177-1372): 1.34e-36: 154: 9.80
+	Hs
		996636 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		CHD3_HUMAN (475-1062): 1.62e-36: 153: 14.78
+	Hs
		449797 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		UHRF2_HUMAN (882-986): 2.33e-24: 112: 27.03
+	Hs
		643389 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		UHRF2_HUMAN (882-986): 2.33e-24: 112: 27.03
+	Hs
		817986 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		CHD3_HUMAN (475-1062): 1.62e-36: 153: 14.78
+	Hs
		449779 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		TITIN_HUMAN (351-1406): 6.27e-16: 86.3: 9.92
+	Hs
		297467 TOX4_HUMAN (91-163): 1.19e-27: 111: 38.36		KDM5C_HUMAN (754-972): 3.88e-26: 119: 20.89
+	Hs
		996841 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		UHRF2_HUMAN (882-986): 2.33e-24: 112: 27.03
+	Hs
		1243837 SOX7_HUMAN (65-181): 1.3e-28: 112: 19.66		KMT2C_HUMAN (830-1420): 8.08e-19: 95.9: 11.64
+	Hs
		996673 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		CHD4_HUMAN (877-960): 3.83e-14: 80.1: 28.57
+	Hs
		818056 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		CHD4_HUMAN (877-960): 3.83e-14: 80.1: 28.57
+	Hs
		152684 SOX7_HUMAN (65-181): 1.3e-28: 112: 19.66		KMT2D_HUMAN (881-1008): 1.91e-10: 68.1: 21.88
+	Hs
		152610 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		KMT2D_HUMAN (881-1008): 1.91e-10: 68.1: 21.88