HitPredict

Interactor 1: TNNC2 (P02585)
Troponin C, skeletal muscle
Gene: TNNC2

Interactor 2: MYO5A (Q9Y4I1)
Unconventional myosin-Va (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myosin-12) (Myoxin)
Gene: MYO5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	EF-hand_7~IQ, EF-hand_7~Myosin_head
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 1855
+	Hs
		993929 TNNC1_HUMAN (1-160): 7.67e-49: 156: 64.60		MYO5A_HUMAN (1-1855): 0: 1278: 100.00
+	Hs
		993927 TNNC1_HUMAN (1-160): 7.67e-49: 156: 64.60		MYO5B_HUMAN (1-1855): 0: 1162: 61.59
+	Hs
		387155 TNNC2_HUMAN (1-160): 6.6e-46: 149: 100.00		MYO5B_HUMAN (1-1855): 0: 1162: 61.59
+	Hs
		516603 CALM3_HUMAN (8-83): 7.67e-15: 69.1: 43.42		MYO5B_HUMAN (1-1855): 0: 1162: 61.59
+	Hs
		516591 CALM3_HUMAN (8-83): 7.67e-15: 69.1: 43.42		MYO5C_HUMAN (1-1855): 0: 1040: 49.17
+	Sc
		449094 CALM_YEAST (10-156): 5.05e-28: 103: 42.18		MYO4_YEAST (6-1047): 0: 871: 39.11
+	Dm
		968552 CALM_DROME (8-83): 9.19e-15: 69.1: 43.42		MYO7A_DROME (8-963): 0: 895: 35.20
+	Dm
		52509 CALL_DROME (18-83): 1.71e-15: 70.9: 46.97		A1Z6Z9_DROME (4-1853): 0: 887: 35.04
+	Dm
		52512 CALM_DROME (8-83): 9.19e-15: 69.1: 43.42		A1Z6Z9_DROME (4-1853): 0: 887: 35.04
+	Hs
		692812 CALL3_HUMAN (8-83): 5.11e-14: 66.8: 38.16		MYO10_HUMAN (7-969): 0: 865: 30.63
+	Sp
		268143 CALM_SCHPO (54-159): 7.77e-09: 53.3: 21.50		MYO51_SCHPO (3-1102): 0: 865: 35.16
+	Sp
		314217 CALM_SCHPO (54-159): 7.77e-09: 53.3: 21.50		MYO52_SCHPO (4-1076): 0: 689: 38.25
+	Hs
		227847 TNNC1_HUMAN (1-160): 7.67e-49: 156: 64.60		MYO1B_HUMAN (66-914): 1e-151: 500: 36.28
+	Hs
		227774 CALM1_HUMAN (8-83): 7.67e-15: 69.1: 43.42		MYO1B_HUMAN (66-914): 1e-151: 500: 36.28
+	Hs
		227775 CALM3_HUMAN (8-83): 7.67e-15: 69.1: 43.42		MYO1B_HUMAN (66-914): 1e-151: 500: 36.28
+	Sc
		449063 CALM_YEAST (10-156): 5.05e-28: 103: 42.18		MYO2_YEAST (1078-1305): 4.82e-09: 63.9: 10.87