Interactor 1: ITB3 (P05106)
Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61)
Gene: ITGB3

Interactor 2: LYN (P07948)
Tyrosine-protein kinase Lyn (EC 2.7.10.2) (Lck/Yes-related novel protein tyrosine kinase) (V-yes-1 Yamaguchi sarcoma viral related oncogene homolog) (p53Lyn) (p56Lyn)
Gene: LYN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 14593208
Identification Methods enzyme linked immunosorbent assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001934 - positive regulation of protein phosphorylation
GO:0005161 - platelet-derived growth factor receptor binding
GO:0005178 - integrin binding
GO:0005634 - nucleus
GO:0005886 - plasma membrane
and 5 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 788
Hs

1 512
+ Rn
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024