HitPredict

Interactor 1: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: RBM33 (Q96EV2)
RNA-binding protein 33 (Proline-rich protein 8) (RNA-binding motif protein 33)
Gene: RBM33

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	23403292, 31527615, unassigned1953
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 1170
+	Hs
		396547 ESR1_HUMAN (1-595): 0: 599: 100.00		KMT2C_HUMAN (328-1135): 4.94e-48: 190: 15.19
+	Hs
		395433 ESR1_HUMAN (1-595): 0: 599: 100.00		MUC1_HUMAN (403-1153): 1.23e-38: 159: 9.56
+	Hs
		396114 ESR1_HUMAN (1-595): 0: 599: 100.00		MDC1_HUMAN (193-1152): 2.63e-23: 109: 9.42
+	Hs
		397115 ESR1_HUMAN (1-595): 0: 599: 100.00		CHD7_HUMAN (269-737): 1.82e-12: 74.6: 10.81
+	Hs
		396643 ESR1_HUMAN (1-595): 0: 599: 100.00		CBP_HUMAN (431-887): 2.28e-12: 73.9: 15.39
+	Hs
		396612 ESR1_HUMAN (1-595): 0: 599: 100.00		TITIN_HUMAN (373-1144): 1.04e-09: 65.6: 11.62
+	Hs
		161392 ESR1_HUMAN (1-595): 0: 599: 100.00		KMT2D_HUMAN (513-1146): 1.34e-09: 64.9: 9.66
+	Hs
		396119 ESR1_HUMAN (1-595): 0: 599: 100.00		NCOA6_HUMAN (213-1154): 5.9e-09: 63: 10.02
+	Hs
		396358 ESR1_HUMAN (1-595): 0: 599: 100.00		ANR11_HUMAN (421-1143): 6.3e-09: 62.9: 10.98
+	Mm
		107050 ESR1_MOUSE (1-595): 0: 570: 88.98		F8VPR5_MOUSE (400-859): 2.52e-11: 70.8: 15.27
+	Hs
		1338263 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		KMT2C_HUMAN (328-1135): 4.94e-48: 190: 15.19
+	Hs
		590324 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		MUC1_HUMAN (403-1153): 1.23e-38: 159: 9.56
+	Hs
		1129670 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		MDC1_HUMAN (193-1152): 2.63e-23: 109: 9.42
+	Hs
		1366935 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		CBP_HUMAN (431-887): 2.28e-12: 73.9: 15.39
+	Hs
		1361882 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		TITIN_HUMAN (373-1144): 1.04e-09: 65.6: 11.62
+	Hs
		161498 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		KMT2D_HUMAN (513-1146): 1.34e-09: 64.9: 9.66
+	Hs
		323896 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		SC31A_HUMAN (460-797): 2.84e-09: 63.9: 14.96
+	Hs
		1130586 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		NCOA6_HUMAN (213-1154): 5.9e-09: 63: 10.02
+	Hs
		1247960 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		ANR11_HUMAN (421-1143): 6.3e-09: 62.9: 10.98
+	Hs
		1273852 ESR2_HUMAN (26-582): 8.93e-136: 408: 45.88		MICA3_HUMAN (614-1146): 8.38e-09: 62.2: 6.85