HitPredict

Interactor 1: PGFRB (P05622)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: Pdgfrb

Interactor 2: NHRF2 (Q9JHL1)
Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (Octs2) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kinase activator protein 1) (TKA-1)
Gene: Nherf2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	16456542
Identification Methods	pull down, chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016324 - apical plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1098 Mm			1 337
+	Hs
		452428 PGFRB_HUMAN (1-1098): 0: 804: 85.26		NHRF2_HUMAN (1-337): 1.42e-77: 242: 91.99
+	Hs
		153861 PGFRB_HUMAN (1-1098): 0: 804: 85.26		NHRF1_HUMAN (2-337): 4.29e-68: 219: 48.59
+	Hs
		153870 PGFRA_HUMAN (3-1098): 0: 718: 42.87		NHRF1_HUMAN (2-337): 4.29e-68: 219: 48.59
+	Hs
		153921 EPHA7_HUMAN (64-980): 9e-153: 483: 12.97		NHRF1_HUMAN (2-337): 4.29e-68: 219: 48.59
+	Hs
		280015 KIT_HUMAN (23-1002): 0: 615: 31.14		MPDZ_HUMAN (6-184): 1.14e-13: 74.3: 18.72
+	Hs
		665393 EPHA3_HUMAN (65-978): 1.15e-168: 524: 14.07		PTN13_HUMAN (89-229): 1.23e-09: 61.9: 19.01
+	Hs
		872433 EPHA5_HUMAN (65-970): 4.71e-159: 500: 15.92		DLG1_HUMAN (52-232): 2.76e-10: 63.5: 17.55
+	Hs
		872431 EPHA5_HUMAN (65-970): 4.71e-159: 500: 15.92		PTN13_HUMAN (89-229): 1.23e-09: 61.9: 19.01
+	Hs
		872496 EPHA5_HUMAN (65-970): 4.71e-159: 500: 15.92		LIN7C_HUMAN (9-87): 6.83e-09: 57: 40.74
+	Hs
		1049958 EPHA7_HUMAN (64-980): 9e-153: 483: 12.97		SCRIB_HUMAN (4-167): 1.88e-13: 73.5: 17.61
+	Hs
		1021499 EPHA7_HUMAN (64-980): 9e-153: 483: 12.97		DLG1_HUMAN (52-232): 2.76e-10: 63.5: 17.55
+	Hs
		1020163 EPHA7_HUMAN (64-980): 9e-153: 483: 12.97		PTN13_HUMAN (89-229): 1.23e-09: 61.9: 19.01
+	Hs
		1072612 EPHA7_HUMAN (64-980): 9e-153: 483: 12.97		LIN7C_HUMAN (9-87): 6.83e-09: 57: 40.74
+	Hs
		153863 FGFR1_HUMAN (9-324): 2.6e-50: 194: 12.57		NHRF1_HUMAN (2-337): 4.29e-68: 219: 48.59
+	Hs
		169176 MUSK_HUMAN (1-698): 4.01e-81: 285: 15.83		SCRIB_HUMAN (4-167): 1.88e-13: 73.5: 17.61
+	Hs
		153881 UFO_HUMAN (2-435): 7.82e-20: 97.6: 10.66		NHRF1_HUMAN (2-337): 4.29e-68: 219: 48.59
+	Hs
		507995 FGFR1_HUMAN (9-324): 2.6e-50: 194: 12.57		SCRIB_HUMAN (4-167): 1.88e-13: 73.5: 17.61
+	Hs
		507970 FGFR1_HUMAN (9-324): 2.6e-50: 194: 12.57		PTN13_HUMAN (89-229): 1.23e-09: 61.9: 19.01
+	Hs
		280018 FGFR3_HUMAN (37-311): 8.59e-31: 132: 12.73		MPDZ_HUMAN (6-184): 1.14e-13: 74.3: 18.72
+	Hs
		674412 UFO_HUMAN (2-435): 7.82e-20: 97.6: 10.66		DLG1_HUMAN (52-232): 2.76e-10: 63.5: 17.55