HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: GRAH (P20718)
Granzyme H (EC 3.4.21.-) (CCP-X) (Cathepsin G-like 2) (CTSGL2) (Cytotoxic T-lymphocyte proteinase) (Cytotoxic serine protease C) (CSP-C)
Gene: GZMH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 246
+	Hs
		458011 TBB3_HUMAN (1-444): 0: 713: 91.44		TRY2_HUMAN (1-244): 2.76e-108: 313: 31.87
+	Hs
		457227 TBB5_HUMAN (1-429): 0: 713: 97.44		GRAH_HUMAN (1-246): 2.57e-103: 301: 100.00
+	Hs
		634754 TBB3_HUMAN (1-444): 0: 713: 91.44		GRAH_HUMAN (1-246): 2.57e-103: 301: 100.00
+	Hs
		1108645 TBB3_HUMAN (1-444): 0: 713: 91.44		KLK6_HUMAN (1-244): 4.75e-102: 298: 31.05
+	Hs
		457179 TBB5_HUMAN (1-429): 0: 713: 97.44		CATG_HUMAN (1-246): 3.48e-101: 296: 57.32
+	Hs
		469792 TBB8_HUMAN (1-427): 0: 702: 90.16		CATG_HUMAN (1-246): 3.48e-101: 296: 57.32
+	Hs
		1108741 TBB3_HUMAN (1-444): 0: 713: 91.44		KLK11_HUMAN (15-244): 7.22e-96: 283: 36.40
+	Hs
		408075 TBB4A_HUMAN (1-427): 0: 708: 100.00		PRSS8_HUMAN (13-246): 1.76e-96: 287: 29.80
+	Hs
		457224 TBB5_HUMAN (1-429): 0: 713: 97.44		TRYB2_HUMAN (10-240): 3.33e-94: 279: 29.30
+	Hs
		628913 TBB3_HUMAN (1-444): 0: 713: 91.44		TRYB2_HUMAN (10-240): 3.33e-94: 279: 29.30
+	Hs
		628912 TBB4B_HUMAN (1-427): 0: 712: 98.60		TRYB2_HUMAN (10-240): 3.33e-94: 279: 29.30
+	Hs
		628918 TBB2B_HUMAN (1-430): 0: 712: 96.74		TRYB2_HUMAN (10-240): 3.33e-94: 279: 29.30
+	Hs
		628914 TBB2A_HUMAN (1-430): 0: 709: 96.28		TRYB2_HUMAN (10-240): 3.33e-94: 279: 29.30
+	Hs
		407979 TBB4A_HUMAN (1-427): 0: 708: 100.00		TRYB2_HUMAN (10-240): 3.33e-94: 279: 29.30
+	Hs
		628915 TBB8_HUMAN (1-427): 0: 702: 90.16		TRYB2_HUMAN (10-240): 3.33e-94: 279: 29.30
+	Hs
		892157 TBB3_HUMAN (1-444): 0: 713: 91.44		GRAK_HUMAN (4-243): 1.91e-45: 154: 37.95
+	Mm
		398302 TBB4B_MOUSE (1-427): 0: 712: 98.60		CFAD_MOUSE (21-240): 6.8e-43: 147: 34.78
+	Hs
		457236 TBB5_HUMAN (1-429): 0: 713: 97.44		PRTN3_HUMAN (20-246): 6.4e-41: 142: 37.45
+	Hs
		407984 TBB4A_HUMAN (1-427): 0: 708: 100.00		PRTN3_HUMAN (20-246): 6.4e-41: 142: 37.45
+	Hs
		449607 TBB8_HUMAN (1-427): 0: 702: 90.16		KLK1_HUMAN (4-243): 1.55e-37: 134: 34.47