HitPredict

Interactor 1: TBB5 (P07437)
Tubulin beta chain (Tubulin beta-5 chain)
Gene: TUBB

Interactor 2: CATG (P08311)
Cathepsin G (CG) (EC 3.4.21.20) [Cleaved into: Cathepsin G, C-terminal truncated form]
Gene: CTSG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005829 - cytosol GO:0035578 - azurophil granule lumen GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 255
+	Hs
		458011 TBB3_HUMAN (1-444): 0: 712: 92.57		TRY2_HUMAN (1-246): 1.18e-111: 322: 33.60
+	Hs
		1108645 TBB3_HUMAN (1-444): 0: 712: 92.57		KLK6_HUMAN (1-244): 5.1e-105: 305: 31.86
+	Hs
		1108741 TBB3_HUMAN (1-444): 0: 712: 92.57		KLK11_HUMAN (18-245): 1.13e-98: 291: 32.07
+	Hs
		469792 TBB8_HUMAN (1-427): 0: 702: 89.70		CATG_HUMAN (1-255): 1.1e-102: 300: 100.00
+	Hs
		634754 TBB3_HUMAN (1-444): 0: 712: 92.57		GRAH_HUMAN (1-245): 8.89e-98: 287: 57.32
+	Hs
		457227 TBB5_HUMAN (1-429): 0: 709: 100.00		GRAH_HUMAN (1-245): 8.89e-98: 287: 57.32
+	Hs
		407981 TBB4A_HUMAN (1-427): 0: 702: 97.42		GRAH_HUMAN (1-245): 8.89e-98: 287: 57.32
+	Hs
		449607 TBB8_HUMAN (1-427): 0: 702: 89.70		KLK1_HUMAN (1-246): 1.63e-97: 287: 31.84
+	Hs
		634763 TBB8_HUMAN (1-427): 0: 702: 89.70		GRAH_HUMAN (1-245): 8.89e-98: 287: 57.32
+	Hs
		408075 TBB4A_HUMAN (1-427): 0: 702: 97.42		PRSS8_HUMAN (3-252): 1.62e-95: 285: 29.47
+	Hs
		663549 TBB8_HUMAN (1-427): 0: 702: 89.70		CMA1_HUMAN (13-245): 2.87e-96: 283: 50.64
+	Hs
		1191976 TBB8_HUMAN (1-427): 0: 702: 89.70		KLK15_HUMAN (14-245): 1.22e-95: 282: 33.60
+	Hs
		892157 TBB3_HUMAN (1-444): 0: 712: 92.57		GRAK_HUMAN (20-242): 3.76e-44: 151: 37.55
+	Hs
		457236 TBB5_HUMAN (1-429): 0: 709: 100.00		PRTN3_HUMAN (20-243): 1.74e-41: 144: 37.50
+	Hs
		407984 TBB4A_HUMAN (1-427): 0: 702: 97.42		PRTN3_HUMAN (20-243): 1.74e-41: 144: 37.50
+	Hs
		664052 TBB8_HUMAN (1-427): 0: 702: 89.70		PRTN3_HUMAN (20-243): 1.74e-41: 144: 37.50
+	Mm
		398302 TBB4B_MOUSE (1-427): 0: 707: 98.36		CFAD_MOUSE (5-238): 2e-36: 131: 32.93