HitPredict

Interactor 1: TBB4A (P04350)
Tubulin beta-4A chain (Tubulin 5 beta) (Tubulin beta-4 chain)
Gene: TUBB4A

Interactor 2: PRTN3 (P24158)
Myeloblastin (EC 3.4.21.76) (AGP7) (C-ANCA antigen) (Leukocyte proteinase 3) (PR-3) (PR3) (Neutrophil proteinase 4) (NP-4) (P29) (Wegener autoantigen)
Gene: PRTN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 444 Hs			1 256
+	Hs
		457236 TBB5_HUMAN (1-429): 0: 713: 97.44		PRTN3_HUMAN (1-256): 8.33e-108: 313: 100.00
+	Hs
		458011 TBB3_HUMAN (1-444): 0: 713: 91.44		TRY2_HUMAN (27-251): 1.07e-97: 287: 33.90
+	Hs
		1108704 TBB3_HUMAN (1-444): 0: 713: 91.44		TMPS5_HUMAN (4-250): 8.91e-92: 279: 29.48
+	Hs
		457693 TBB5_HUMAN (1-429): 0: 713: 97.44		TMPS5_HUMAN (4-250): 8.91e-92: 279: 29.48
+	Hs
		997509 TBB4B_HUMAN (1-427): 0: 712: 98.60		TMPS5_HUMAN (4-250): 8.91e-92: 279: 29.48
+	Hs
		1118591 TBB2A_HUMAN (1-430): 0: 709: 96.28		TMPS5_HUMAN (4-250): 8.91e-92: 279: 29.48
+	Hs
		408162 TBB4A_HUMAN (1-427): 0: 708: 100.00		TMPS5_HUMAN (4-250): 8.91e-92: 279: 29.48
+	Hs
		1414189 TBB6_HUMAN (1-433): 0: 707: 93.07		TMPS5_HUMAN (4-250): 8.91e-92: 279: 29.48
+	Hs
		408075 TBB4A_HUMAN (1-427): 0: 708: 100.00		PRSS8_HUMAN (18-256): 1.22e-90: 273: 26.52
+	Hs
		1108645 TBB3_HUMAN (1-444): 0: 713: 91.44		KLK6_HUMAN (9-250): 1.21e-89: 267: 30.56
+	Hs
		457179 TBB5_HUMAN (1-429): 0: 713: 97.44		CATG_HUMAN (22-248): 1.64e-41: 144: 37.55
+	Hs
		663549 TBB8_HUMAN (1-427): 0: 702: 90.16		CMA1_HUMAN (23-248): 3.94e-46: 155: 40.25
+	Hs
		457227 TBB5_HUMAN (1-429): 0: 713: 97.44		GRAH_HUMAN (22-250): 3.28e-41: 143: 37.08
+	Hs
		634754 TBB3_HUMAN (1-444): 0: 713: 91.44		GRAH_HUMAN (22-250): 3.28e-41: 143: 37.08
+	Hs
		407981 TBB4A_HUMAN (1-427): 0: 708: 100.00		GRAH_HUMAN (22-250): 3.28e-41: 143: 37.08
+	Hs
		469792 TBB8_HUMAN (1-427): 0: 702: 90.16		CATG_HUMAN (22-248): 1.64e-41: 144: 37.55
+	Hs
		634763 TBB8_HUMAN (1-427): 0: 702: 90.16		GRAH_HUMAN (22-250): 3.28e-41: 143: 37.08
+	Hs
		892157 TBB3_HUMAN (1-444): 0: 713: 91.44		GRAK_HUMAN (27-247): 7.7e-34: 124: 34.57
+	Mm
		398302 TBB4B_MOUSE (1-427): 0: 712: 98.60		CFAD_MOUSE (10-245): 1.33e-33: 124: 34.52
+	Hs
		449607 TBB8_HUMAN (1-427): 0: 702: 90.16		KLK1_HUMAN (15-247): 1.28e-31: 119: 33.96