Interactor 1: LCK (P06240)
Proto-oncogene tyrosine-protein kinase LCK (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: STAP1 (Q9JM90)
Signal-transducing adaptor protein 1 (STAP-1) (Stem cell adaptor protein 1)
Gene: STAP1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 10679268
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SH2, SH2~SH2, PH~SH3_1, SH2~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0010628 - positive regulation of gene expression
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 509
Mm

1 297
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024