Interactor 1: HXKA (P04806)
Hexokinase-1 (EC 2.7.1.1) (Hexokinase PI) (Hexokinase-A)
Gene: HXK1

Interactor 2: HXKA (P04806)
Hexokinase-1 (EC 2.7.1.1) (Hexokinase PI) (Hexokinase-A)
Gene: HXK1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.821

The method score is based on:

Property Details
Experiments 37196001, 10877063, unassigned1933
Identification Methods biochemical, fluorescent resonance energy transfer, dihydrofolate reductase reconstruction
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hexokinase_1~Hexokinase_1, Hexokinase_1~Hexokinase_2, Hexokinase_2~Hexokinase_2
Common GO terms GO:0001678 - intracellular glucose homeostasis
GO:0004340 - glucokinase activity
GO:0004396 - hexokinase activity
GO:0005524 - ATP binding
GO:0005536 - D-glucose binding
and 12 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 485
Sc

1 485
+ Sc
+ Sc
+ Hs
+ Mm
+ At
+ Hs
+ Mm
+ At
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025