HitPredict

Interactor 1: HXKB (P04807)
Hexokinase-2 (EC 2.7.1.1) (Hexokinase PII) (Hexokinase-B)
Gene: HXK2

Interactor 2: HXKB (P04807)
Hexokinase-2 (EC 2.7.1.1) (Hexokinase PII) (Hexokinase-B)
Gene: HXK2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 9566913, 37196001, unassigned1933
Identification Methods pull down, biochemical, affinity chromatography technology, dihydrofolate reductase reconstruction
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hexokinase_1~Hexokinase_1, Hexokinase_1~Hexokinase_2, Hexokinase_2~Hexokinase_2
Common GO terms GO:0001678 - intracellular glucose homeostasis
GO:0004340 - glucokinase activity
GO:0004396 - hexokinase activity
GO:0005524 - ATP binding
GO:0005536 - D-glucose binding
and 16 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 486
Sc

1 486
+ Sc
+ Sc
+ Mm
+ Hs
+ Hs
+ At
+ Mm
+ At
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 11Aug2025