HitPredict

Interactor 1: USF1 (P22415)
Upstream stimulatory factor 1 (Class B basic helix-loop-helix protein 11) (bHLHb11) (Major late transcription factor 1)
Gene: USF1

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 103
+	Hs
		917336 USF2_HUMAN (4-304): 1.97e-82: 254: 51.19		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		252913 MITF_HUMAN (108-304): 8.28e-39: 145: 21.74		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Mm
		348414 MYC_MOUSE (110-290): 4.19e-38: 142: 22.28		H4_MOUSE (1-103): 1.38e-48: 151: 100.00
+	Hs
		917972 MLXPL_HUMAN (87-303): 1.32e-36: 140: 18.55		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		346438 MYC_HUMAN (110-288): 4.45e-37: 139: 21.98		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		585646 TFE3_HUMAN (86-303): 4.46e-36: 138: 19.49		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Mm
		918249 TFE3_MOUSE (86-303): 2.04e-35: 136: 18.64		H4_MOUSE (1-103): 1.38e-48: 151: 100.00
+	Hs
		379230 MYCN_HUMAN (106-286): 7.41e-35: 133: 19.13		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		738952 SRBP1_HUMAN (77-280): 3.68e-29: 119: 19.73		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		918090 MLX_HUMAN (117-299): 7.95e-31: 119: 21.39		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		585112 TFEB_HUMAN (135-302): 8.95e-28: 113: 20.83		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		379768 MYCN_HUMAN (106-286): 7.41e-35: 133: 19.13		H4G_HUMAN (1-98): 1.04e-38: 126: 84.69
+	Sc
		356426 RTG3_YEAST (108-310): 1.11e-29: 119: 16.91		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		917801 MNT_HUMAN (100-292): 3.02e-21: 95.9: 15.46		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		898095 MAX_HUMAN (180-298): 1.61e-20: 88.2: 31.09		H4_HUMAN (1-103): 1.38e-48: 151: 100.00