Protein: HXK3
Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III) (Hexokinase-C)

Gene: HXK3, HK3
Organism: Homo sapiens
Interactions: 36
UniProt ID: P52790

Gene Ontology (top 5):
GO:0001678 - intracellular glucose homeostasis
GO:0004340 - glucokinase activity
GO:0004396 - hexokinase activity
GO:0005524 - ATP binding
GO:0005536 - D-glucose binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

621456

HXK1
Hexokinase-1

3

14

High-throughput

0.855

High

914070

HXK2
Hexokinase-2

2

14

High-throughput

0.811

High

914151

HKDC1
Hexokinase HKDC1

2

14

High-throughput

0.811

High

914146

NPC2
NPC intracellular cholesterol transporter 2

2

0

High-throughput

0.602

High

269099

MITF
Microphthalmia-associated transcription factor

1

1

High-throughput

0.541

High

914147

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

High-throughput

0.541

High

210732

KLK10
Kallikrein-10

1

2

High-throughput

0.536

High

269950

AUXI
Auxilin

1

1

High-throughput

0.536

High

914156

TPC2
Two pore channel protein 2

1

1

High-throughput

0.536

High

617206

ATF4
Cyclic AMP-dependent transcription factor ATF-4

1

0

High-throughput

0.518

High

843405

HD
Huntingtin

1

1

High-throughput

0.515

High

914159

KLK6
Kallikrein-6

1

2

High-throughput

0.515

High

914164

FUND2
FUN14 domain-containing protein 2

1

0

High-throughput

0.513

High

914160

INP4A
Inositol polyphosphate-4-phosphatase type I A

1

0

High-throughput

0.493

High

875879

TCPE
T-complex protein 1 subunit epsilon

1

0

High-throughput

0.493

High

896708

DYN2
Dynamin-2

1

0

High-throughput

0.493

High

914145

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

914148

FOXL1
Forkhead box protein L1

1

6

High-throughput

0.489

High

914153

FOXI2
Forkhead box protein I2

1

6

High-throughput

0.489

High

914155

RDHE2
Epidermal retinol dehydrogenase 2

1

1

High-throughput

0.489

High

914161

FOXB1
Forkhead box protein B1

1

6

High-throughput

0.489

High

914152

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

914149

CUL3
Cullin-3

1

4

High-throughput

0.445

High

893766

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

914163

SC22C
Vesicle-trafficking protein SEC22c

2

0

High-throughput

0.318

High

48136

IFT56
Intraflagellar transport protein 56

2

0

High-throughput

0.313

High

638175

S1PR1
Sphingosine 1-phosphate receptor 1

1

0

High-throughput

0.279

Low

914144

T2R50
Taste receptor type 2 member 50

1

0

High-throughput

0.279

Low

914150

LAGE3
EKC/KEOPS complex subunit LAGE3

1

0

High-throughput

0.279

Low

914157

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.279

Low

914162

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.279

Low

914165

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.279

Low

301375

WFS1
Wolframin

1

0

High-throughput

0.268

Low

914154

Q86V38
Atrophin 1

1

0

High-throughput

0.268

Low

914158

APBB2
Amyloid beta precursor protein binding family B member 2

1

0

High-throughput

0.268

Low

914166

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025