HitPredict

Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3

Interactor 2: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0007015 - actin filament organization
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 285 Hs			1 191
+	Hs
		932008 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHOH_HUMAN (1-191): 2.74e-95: 276: 100.00
+	Hs
		451225 TPM1_HUMAN (2-285): 2.54e-44: 153: 91.20		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		418937 TPM3_HUMAN (1-285): 3.63e-44: 153: 100.00		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		925177 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		1076834 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOH_HUMAN (1-191): 2.74e-95: 276: 100.00
+	Hs
		931991 TPM4_HUMAN (43-285): 1.76e-33: 124: 69.96		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		916101 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		925356 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		564571 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		894128 MRCKG_HUMAN (3-285): 1.48e-14: 75.7: 10.65		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		925766 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		564758 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		894628 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		545725 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07
+	Hs
		892702 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81
+	Hs
		951494 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		901094 MRCKB_HUMAN (12-285): 1.02e-11: 67.2: 14.92		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38