Interactor 1: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.656

The method score is based on:

Property Details
Experiments 35271311, 29930177, 33239621
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006457 - protein folding
and 4 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 724
Hs

1 840
+ Hs
+ Hs
+ Hs
+ Ce
+ Sc
+ Sc
+ Sc
+ Sc
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024