HitPredict

Interactor 1: RU2B (P08579)
U2 small nuclear ribonucleoprotein B'' (U2 snRNP B'')
Gene: SNRPB2

Interactor 2: SPF45 (Q96I25)
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)
Gene: RBM17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	35271311, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 225 Hs			1 401
+	Mm
		857354 TIA1_MOUSE (2-160): 4.64e-17: 80.5: 14.29		SPF45_MOUSE (1-401): 3.28e-154: 442: 98.27
+	Dm
		795445 SNRPA_DROME (1-225): 1.52e-43: 147: 64.44		Q7PL82_DROME (51-397): 7.74e-86: 267: 36.73
+	Hs
		441283 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		446632 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Sp
		143386 RU1A_SCHPO (2-225): 2.35e-42: 145: 36.40		RSD1_SCHPO (130-392): 3.55e-53: 188: 19.63
+	Hs
		643504 PTBP1_HUMAN (5-224): 4.18e-17: 81.2: 16.07		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1020258 ELAV2_HUMAN (128-224): 1.33e-15: 76.3: 19.61		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1054312 ELAV3_HUMAN (120-224): 1.38e-15: 76.3: 18.18		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		235862 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		1031328 PABP4_HUMAN (148-225): 1.72e-13: 70.9: 19.28		RBM39_HUMAN (88-394): 1.66e-72: 237: 13.76
+	Hs
		446510 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		446829 SNRPA_HUMAN (2-225): 2.91e-42: 146: 48.56		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		212094 RU2B_HUMAN (1-225): 5.14e-51: 166: 100.00		HTSF1_HUMAN (305-388): 4.02e-17: 85.4: 27.78
+	Hs
		641622 PTBP1_HUMAN (5-224): 4.18e-17: 81.2: 16.07		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Mm
		641996 TIA1_MOUSE (2-160): 4.64e-17: 80.5: 14.29		U2AF2_MOUSE (244-397): 2.5e-36: 140: 23.93
+	Hs
		235717 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		641756 PABP4_HUMAN (148-225): 1.72e-13: 70.9: 19.28		U2AF2_HUMAN (244-397): 2.42e-36: 140: 23.93
+	Hs
		1355614 PTBP2_HUMAN (1-224): 4.63e-16: 78.2: 17.98		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		236122 HNRPQ_HUMAN (4-224): 8.43e-14: 71.6: 20.00		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67
+	Hs
		1031490 PABP4_HUMAN (148-225): 1.72e-13: 70.9: 19.28		PUF60_HUMAN (131-398): 8.05e-33: 131: 16.67