HitPredict

Interactor 1: RASK (P08644)
GTPase KRas (EC 3.6.5.2) (K-Ras 2) (Ki-Ras) (c-K-ras) (c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Gene: Kras

Interactor 2: ITM2B (Q5XIE8)
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]
Gene: ITM2B

Species: Rattus norvegicus

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29476059
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 189 Rn			1 266
+	Hs
		349742 RASH_HUMAN (1-188): 3.11e-87: 256: 86.77		ITM2B_HUMAN (1-266): 1.32e-148: 417: 96.24
+	Hs
		349014 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		ITM2B_HUMAN (1-266): 1.32e-148: 417: 96.24
+	Rn
		1140267 RAB1A_RAT (4-187): 3.4e-76: 228: 34.87		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		102472 G3V6H0_RAT (4-187): 5.12e-75: 225: 32.47		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		489853 RAB1B_RAT (4-187): 1.1e-74: 224: 32.47		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Hs
		350698 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		ITM2B_HUMAN (1-266): 1.32e-148: 417: 96.24
+	Hs
		348946 RASN_HUMAN (1-189): 3.17e-86: 253: 86.24		ITM2C_HUMAN (1-265): 1.17e-121: 349: 42.75
+	Hs
		350585 RASK_HUMAN (1-189): 6.74e-78: 232: 98.94		ITM2C_HUMAN (1-265): 1.17e-121: 349: 42.75