Interactor 1: TPM3 (P06753)
Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5)
Gene: TPM3
Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 1.00 | 0.959 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781, 38334954, 32296183, 34349018, 35235311, 35575683, unassigned1304 |
| Identification Methods | affinity chromatography technology, cross-linking study, two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Tropomyosin~Tropomyosin |
| Common GO terms | GO:0001725 - stress fiber GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005862 - muscle thin filament tropomyosin GO:0005884 - actin filament and 4 others more... |
| Homologous interactions | 15 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
