Interactor 1: TPM2 (P07951)
Tropomyosin beta chain (Beta-tropomyosin) (Tropomyosin-2)
Gene: TPM2
Interactor 2: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.973 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 30021884, 3857586, 35575683, 28524877, 38334954, 26186194, 28514442, 33961781, 35235311, 26414014 |
| Identification Methods | proximity labelling technology, pull down, cross-linking study, affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Tropomyosin~Tropomyosin |
| Common GO terms | GO:0003779 - actin binding GO:0005829 - cytosol GO:0005862 - muscle thin filament tropomyosin GO:0005884 - actin filament GO:0007015 - actin filament organization and 5 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
