Interactor 1: TPM1 (P58771)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: TPM4 (Q6IRU2)
Tropomyosin alpha-4 chain (Tropomyosin-4)
Gene: TPM4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29199018
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Tropomyosin~Tropomyosin
Common GO terms GO:0005737 - cytoplasm
GO:0015629 - actin cytoskeleton
GO:0042803 - protein homodimerization activity
GO:0046982 - protein heterodimerization activity
GO:0051015 - actin filament binding
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 284
Mm

1 248
+ Hs
+ Dm
+ Gg
+ Rn
+ Hs
+ Mm
+ Gg
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025