Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: PAF1 (Q8N7H5)
RNA polymerase II-associated factor 1 homolog (hPAF1) (Pancreatic differentiation protein 2)
Gene: PAF1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 29721183
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005654 - nucleoplasm
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0071222 - cellular response to lipopolysaccharide
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 215
Hs

1 531
+ Hs
+ Hs
+ Hs
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024