HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: DC2I1 (Q8WVS4)
Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60)
Gene: DYNC2I1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	32867128
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 1066
+	Hs
		643346 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		EIF3A_HUMAN (6-577): 6.47e-31: 134: 11.34
+	Hs
		617319 SP100_HUMAN (25-178): 1.23e-34: 131: 87.66		NIPBL_HUMAN (2-453): 1.66e-31: 136: 16.96
+	Hs
		996715 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		NIPBL_HUMAN (2-453): 1.66e-31: 136: 16.96
+	Hs
		996665 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		EIF3A_HUMAN (6-577): 6.47e-31: 134: 11.34
+	Hs
		818155 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		NIPBL_HUMAN (2-453): 1.66e-31: 136: 16.96
+	Hs
		449804 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		DDX23_HUMAN (12-372): 2.35e-12: 73.5: 13.80
+	Hs
		1049622 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		EIF3A_HUMAN (6-577): 6.47e-31: 134: 11.34
+	Hs
		996722 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		ANR11_HUMAN (15-446): 2.69e-13: 76.9: 11.72
+	Hs
		996869 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		DDX23_HUMAN (12-372): 2.35e-12: 73.5: 13.80
+	Hs
		551635 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		DESP_HUMAN (1-554): 5.69e-14: 79.3: 12.35
+	Hs
		817913 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		MAP1A_HUMAN (13-457): 6.38e-14: 78.9: 9.80
+	Hs
		818268 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		BD1L1_HUMAN (23-488): 4.25e-13: 76.5: 12.53
+	Mm
		93555 SOX17_MOUSE (4-90): 2.66e-22: 95.1: 18.39		DESP_MOUSE (1-554): 2.62e-14: 80.4: 11.65
+	Hs
		551812 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		DESP_HUMAN (1-554): 5.69e-14: 79.3: 12.35
+	Hs
		1246354 CIC_HUMAN (3-96): 2.76e-12: 67: 22.34		THOC2_HUMAN (10-404): 3.64e-10: 66.5: 14.15
+	Hs
		567757 UBF1_HUMAN (49-205): 2.54e-09: 58.2: 20.00		DDX23_HUMAN (12-372): 2.35e-12: 73.5: 13.80