HitPredict

Interactor 1: TPM1 (P09493)
Tropomyosin alpha-1 chain (Alpha-tropomyosin) (Tropomyosin-1)
Gene: TPM1

Interactor 2: PP1B (P62140)
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PP-1B) (PPP1CD) (EC 3.1.3.16) (EC 3.1.3.53)
Gene: PPP1CB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 327
+	Dm
		419100 TPM1_DROME (1-281): 3.07e-56: 186: 44.78		PP1B_DROME (1-322): 0: 568: 90.37
+	Hs
		418931 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		434366 TPM2_HUMAN (1-284): 1.39e-38: 138: 85.56		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		110799 H7BYY1_HUMAN (41-284): 8.14e-35: 127: 70.49		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Hs
		418899 TPM3_HUMAN (1-284): 1.02e-43: 152: 91.20		PP1G_HUMAN (1-327): 0: 569: 86.89
+	Hs
		906405 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		PP1B_HUMAN (1-327): 0: 597: 100.00
+	Dm
		451124 TPM2_DROME (1-282): 7.75e-35: 128: 49.29		PP1B_DROME (1-322): 0: 568: 90.37
+	Hs
		737733 TPM4_HUMAN (42-284): 3.76e-33: 123: 68.72		PP1G_HUMAN (1-327): 0: 569: 86.89